Paul Pistell | Towson University


Before coming to Towson, Dr. Pistell spent four years at the Pennington Biomedical
Research Center conducting research in the Laboratory of Nutritional Neuroscience
and Aging, and supervising the behavioral core.


Research Interests

Over his 20 years involved in preclinical research, Dr. Pistell has had the opportunity
to be involved a wide range of research topics utilizing a wide array of behavioral
tasks. In recent years his research has focused on several areas. As an overarching
theme, his lab conducts studies to evaluate behavioral outcomes and therapeutic interventions
during normal and abnormal aging in rodent models. More specifically, they are interested
in assessing the potential of nutritional or pharmacological interventions to improve
functional outcomes during aging. As part of this process, they also are interested
in the underlying neurobiological and biochemical mechanisms associated with learning/memory
and motor function.


Selected Publications

Gupta A, Lacoste B, Pistell PJ, Ingram DK, Hamel E, Alaoui-Jamali MA, Szarek WA, Vlahakis JZ, Jie S, Song W, Schipper
HM. (2014). Neurotherapeutic effects of novel HO-1 inhibitors in vitro and in a transgenic
mouse model of Alzheimer’s disease. Journal of Neurochemistry, 131(6), 778-790. doi:

Pistell PJ, Duffy KB, Kelley-Bell B, Spangler EL, Ingram DK. (2014). Phosphodiesterase inhibition
facilitates cognitive restoration in rodent models of age-related memory decline.
Neurorehabilitation, 34(1), 101-111. doi: 10.3233/NRE-131022.

READ:  Office of Technology Services

Zhou J, Keenan MK, Fernandez-Kim SO, Pistell PJ, Ingram DK, Raggio AM, Shen L, Zhang H, McCutcheon KL, Tulley RL, Blackman MR, Keller
JN, Martin RJ. (2013). Dietary resistant starch improves selected brain and behavioral
functions in adult and aged rodents. Molecular Nutrition and Food Research, 57(11),
2071-2074. doi: 10.1002/mnfr.201300135.

Pistell PJ, Spangler EL, Kelly-Bell B, Miller MG, de Cabo R, Ingram DK. (2012). Age-associated
learning and memory deficits in two mouse versions of the Stone T-maze. Neurobiology
of Aging, 33(10), 2431-2439. doi: 10.1016/j.neurobiolaging.2011.12.004.

Pistell PJ, Ingram DK. (2010). Development of a water-escape motivated version of the Stone
T-maze for mice. Neuroscience. 166(1), 61-72. doi: 10.1016/j.neuroscience.2009.12.029.

Pistell PJ, Morrison CD, Gupta S, Knight AG, Keller JN, Ingram DK, Bruce-Keller AJ. (2010).
Cognitive impairment following high fat diet consumption is associated with brain
inflammation. Journal of Neuorimmunology, 219(1-2), 25-32. doi: 10.1016/j.jneuroim.2009.11.010.

Courses Taught

  • PSYC 309: Psychopharmacology
  • PSYC 314: Research Methods
  • PSYC 460: Ethology and Comparative Psychology
  • PSYC 465: Physiological Psychology

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